Coronary artery bypass grafting is a major cardiac surgical procedure performed under general anaesthesia, typically lasting three to six hours depending on the number of bypasses required. In conventional on-pump surgery, the heart is arrested and cardiopulmonary bypass (the heart-lung machine) maintains systemic circulation while the surgeon constructs each bypass conduit. The left internal mammary (thoracic) artery is the preferred conduit for the left anterior descending artery bypass due to its superior long-term patency; the great saphenous vein from the leg and the radial artery from the forearm are used as supplementary conduits. In off-pump (beating-heart) surgery, bypasses are constructed on the still-beating heart using mechanical stabilisers, avoiding cardiopulmonary bypass.
Patient selection is based on coronary angiography demonstrating significant stenosis in multiple vessels or in critical locations (left main disease, proximal three-vessel disease) where complete revascularisation by percutaneous coronary intervention is not appropriate. Left ventricular function, the presence of diabetes, and the extent of disease influence the decision between surgical and percutaneous approaches. Pre-operative optimisation of cardiac medications, renal function, and glycaemic control is important for reducing peri-operative risk.
Post-operatively, patients are nursed in the intensive care unit for twenty-four to forty-eight hours before transfer to a high-dependency ward. Hospital stay is typically five to eight days. Sternal healing requires approximately six to eight weeks during which upper extremity loading is restricted. Patients should not drive for four to six weeks. Full functional recovery and return to normal activity typically takes two to three months. Cardiac rehabilitation — a structured exercise and education programme — is an evidence-based component of post-CABG care that significantly reduces re-admission rates and improves long-term outcomes.